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I Spigelman Selected Research

Hyperalgesia

1/2012Intradermal injection of Botulinum toxin type A alleviates infraorbital nerve constriction-induced thermal hyperalgesia in an operant assay.
4/2009Botulinum toxin type a (150 kDa) decreases exaggerated neurotransmitter release from trigeminal ganglion neurons and relieves neuropathy behaviors induced by infraorbital nerve constriction.

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I Spigelman Research Topics

Disease

2Hyperalgesia
01/2012 - 04/2009
1Shock
05/2023
1Alcoholism (Alcohol Abuse)
01/2016
1Chronic Pain
04/2009
1Neuralgia (Stump Neuralgia)
04/2009
1Trigeminal Nerve Diseases (Trigeminal Nerve Disorders)
04/2009
1Diabetic Neuropathies (Diabetic Neuropathy)
03/2006
1Temporal Lobe Epilepsy
12/2000
1Status Epilepticus (Complex Partial Status Epilepticus)
12/2000
1Inflammation (Inflammations)
07/2000

Drug/Important Bio-Agent (IBA)

2incobotulinumtoxinAFDA Link
01/2012 - 04/2009
1Ethanol (Ethyl Alcohol)IBA
05/2023
1Interleukin-10 (Interleukin 10)IBA
01/2016
1Type A Botulinum Toxins (Botox)FDA Link
01/2012
1salicylhydroxamic acid (SHAM)IBA
01/2012
1Neurotransmitter Agents (Neurotransmitter)IBA
04/2009
1Nerve Growth Factor (NGF)IBA
03/2006
1Kainic Acid (Kainate)IBA
12/2000
1Pilocarpine (Ocusert)FDA LinkGeneric
12/2000
1TurpentineIBA
07/2000
1Substance PIBA
07/2000

Therapy/Procedure

2Intradermal Injections
01/2012 - 04/2009